Mucosal melanocytic macules Treatment of labial melanotic macules on the lip. These are benign spots that appear on the lips for no apparent reason. The causes are mostly genetic, but similar spots can appear in smokers, after Lip Pigmentation Treatment in Singapore A bothersome lip lesion (labial melanotic macule) was effectively removed using our advanced Q10 Brightlase treatment. This quick, safe, and precise procedure left our patient with smooth, lesion free lips. Q10 Brightlase is Removal of lip pigmentation with our Alma Q laser. Such lip spots (aka labial melanotic macules) appear for no apparent reason. Similar spots can appear due to smoking, sun damage, drug reactions,